NUR 4190 Module 5 Evidence Synthesis Paper Example

Reviewed by Gwyneth Ollerton, MSN, RN Thomas Edison State University Updated October 2026

In NUR 4190 Module 5 the studies stop being appraised one at a time and start being weighed together, and this sample shows how that synthesis reads when it is finished. Prepared for the TESU BSN research course, Exploring Evidence-Based Practice and Research in Nursing, it combines a meta-analysis, three randomized trials, a Cochrane review and a qualitative study on cold and vibration for children's venipuncture pain. An evidence table ordered by level comes first, then sections on strength and consistency, on the gaps the studies leave, and on how qualitative findings shape the way a device should be introduced. The course is coded NUR-4190 at TESU. The paper ends with a stated verdict that a practice change proposal can build on.

CourseNUR-4190 Exploring Evidence-Based Practice and Research in Nursing
ModuleModule 5
Paper typeEvidence synthesis
LengthAbout 1,067 words, 6 pages
FormatAPA 7 student paper
SchoolThomas Edison State University
ProgramBachelor of Science in Nursing
UpdatedOctober 2026

Free sample paper for NUR 4190 Module 5

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What Six Studies Say Together: Synthesizing the Evidence on Cold and Vibration for School-Age Children's Venipuncture Pain

Student Name

Bachelor of Science in Nursing, Thomas Edison State University

NUR-4190: Exploring Evidence-Based Practice and Research in Nursing

Mentor Name

Month Day, Year

What this page is doingThe phrase what six studies say together announces a synthesis rather than a series of summaries, which is the distinction the module is built to test. The title also restates the population, so a reader can check every study in the paper against it.
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What Six Studies Say Together: Synthesizing the Evidence on Cold and Vibration for School-Age Children's Venipuncture Pain

The earlier modules of this course produced a clinical question, a documented search, and appraisals of one randomized trial and one qualitative study. This paper brings the evidence together. The question it answers is whether school-age clinic patients, five to twelve years old, report less pain at their monitoring draws when the nurse adds a cold and vibration device to the distraction we already use. Six sources are synthesized: one systematic review with meta-analysis, three randomized trials, one Cochrane review of the comparison condition and one qualitative study. The goal is not to describe each source again but to state what the body of evidence supports, how strongly, and with what reservations.

The Evidence at a Glance

The table summarizes the six sources by design, population, comparison, outcome and main finding. It is arranged from the highest level of evidence to the lowest, following the hierarchy in Melnyk and Fineout-Overholt (2023).

Reading across the table, two patterns stand out. First, every comparison of the device with no active treatment or with standard care favored the device, whether pain was reported by the child, a parent or an observer. Second, both comparisons of the device with another active treatment, a lidocaine patch in one trial and a cold spray in another, found the device less effective on pain. These two patterns are not contradictory. They describe a device that clearly beats doing nothing extra and does not quite match a topical anesthetic that has had time to work.

SourceDesign and levelPopulationComparisonMain pain finding
Ballard et al. (2019)Systematic review and meta-analysis of 7 trials, Level IAges 3 to 18, needle procedures, 1,138 participants in the reviewDevice vs no treatmentLarge reduction in self-reported pain (SMD -1.11) and in parent and observer reports
Semerci et al. (2023)Randomized trial, single blind, Level II161 children aged 5 to 12, emergency department venipunctureDevice vs cold spray vs standard careBoth active groups lower than control; cold spray lower than device
Lescop et al. (2021)Randomized non-inferiority trial, Level II215 children aged 4 to 15, vaccination or venipunctureDevice vs lidocaine patchMean pain 2.04 vs 1.42 of 10; non-inferiority not shown
Zhou et al. (2025)Randomized factorial trial, Level II130 children aged 2 to 7, venipunctureCold, vibration, both, inactive deviceAll active groups lower; combination lowest
Birnie et al. (2018)Cochrane systematic review, Level I59 trials, ages 2 to 19Psychological interventions vs controlDistraction reduces self-reported pain; evidence low quality
Sørensen et al. (2021)Qualitative interviews and focus groups, Level VIChildren 6 to 17 and parents, home injectionsNot applicableFear peaks before the needle; some children prefer control to distraction
What this page is doingA summary table that orders sources by level of evidence lets the mentor see the whole body of evidence at once. The paragraph after the table does the synthesis work by naming patterns across studies, which is exactly what separates this module from the appraisal modules.
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Strength and Consistency

The strongest single source is the meta-analysis by Ballard et al. (2019), which pooled randomized trials and found a large effect on self-reported pain. Its authors rated the quality of evidence as limited, mainly because the trials had high or unclear risk of bias in blinding and allocation, which is unavoidable to some degree when one group holds a cold, buzzing device. The newer trials share that weakness. Zhou et al. (2025) could not blind families, and Semerci et al. (2023) blinded only one party. Still, the direction of effect is consistent across countries, settings and age groups, and consistency across imperfect studies is itself a form of evidence.

The most directly applicable trial is Semerci et al. (2023), because its children were aged five to twelve, the same range as my question, and because pain was self-reported. That trial supports the device over standard care, which is close to my comparison, though its setting was an emergency department rather than a clinic with familiar patients. Lescop et al. (2021) also included school-age children and self-report, and its result matters for a different reason: in a clinic where many families already choose a lidocaine product, the device should be offered as an alternative for children who arrive without time for the cream, not as a replacement for it.

What this page is doingThis section judges the body of evidence on strength, consistency and applicability, and it is honest about shared weaknesses. Mentors frequently grade synthesis on whether the student can say how confident the evidence allows them to be, not only what it shows.
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Where the Evidence Is Thin

The literature leaves three questions open for this clinic. No trial in the set was conducted in an outpatient specialty clinic where the same children return many times, so it is unknown whether the benefit grows, holds or fades with repeated use. Few studies report how the device affects procedure time or first-attempt success, which matter to a busy draw room; the meta-analysis found no significant difference in first-attempt success, which is reassuring but based on limited data. Finally, the trials measure pain during a single procedure, while the qualitative study suggests that the anticipation before the needle may be the worst part for children with chronic illness. A device applied only at the moment of the stick may not address that anticipation unless children are given a hand in when and how it starts.

What this page is doingNaming gaps precisely, and explaining why each one matters for the writer's setting, is often the difference between a good and an excellent synthesis. It also prepares the evaluation plan in the next module, which will need to measure what the literature has not.
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Integrating the Qualitative Evidence

The qualitative findings do not change the verdict on effectiveness, but they shape how the device should be used. Sørensen et al. (2021) found that the moment before the needle caused the most fear, that parents felt underprepared, and that some children disliked distraction because they wanted to feel in control. Birnie et al. (2018) show that distraction still reduces pain on average, which supports keeping it as part of usual care. Taken together, these sources suggest a combined approach in which the child is offered the device, invited to help place it or switch it on, and supported with distraction if they want it rather than by default. Parents can be shown the approach at the first visit so they can coach their child at later visits.

What this page is doingIntegrating qualitative and quantitative evidence into one recommendation is the hardest synthesis move and the one most rubrics reserve for the top band. The writer uses the qualitative study to shape implementation without overstating it as proof of effect.
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Verdict

The body of evidence supports adding a cold and vibration device to usual distraction for school-age children having venipuncture. The support is consistent and moderately strong for reducing pain compared with standard care, weaker in quality because of unavoidable blinding problems, and indirect for the specific setting of an outpatient clinic with repeat patients. The device appears less effective than a topical anesthetic that has had time to work, so it should complement that option rather than replace it. The next module will propose a practice change on this basis and plan how to evaluate it in a setting the existing studies do not cover.

References

Ballard, A., Khadra, C., Adler, S., Trottier, E. D., & Le May, S. (2019). Efficacy of the Buzzy device for pain management during needle-related procedures: A systematic review and meta-analysis. The Clinical Journal of Pain, 35(6), 532-543. https://doi.org/10.1097/AJP.0000000000000690

Birnie, K. A., Noel, M., Chambers, C. T., Uman, L. S., & Parker, J. A. (2018). Psychological interventions for needle-related procedural pain and distress in children and adolescents. Cochrane Database of Systematic Reviews, 2018(10), Article CD005179. https://doi.org/10.1002/14651858.CD005179.pub4

Lescop, K., Joret, I., Delbos, P., Briend-Godet, V., Blanchi, S., Brechet, C., Galivel-Voisine, A., Coudol, S., Volteau, C., Riche, V.-P., & Cartron, E. (2021). The effectiveness of the Buzzy device to reduce or prevent pain in children undergoing needle-related procedures: The results from a prospective, open-label, randomised, non-inferiority study. International Journal of Nursing Studies, 113, 103803. https://doi.org/10.1016/j.ijnurstu.2020.103803

Melnyk, B. M., & Fineout-Overholt, E. (2023). Evidence-based practice in nursing and healthcare: A guide to best practice (5th ed.). Wolters Kluwer.

Semerci, R., Akarsu, Ö., & Kılıç, D. (2023). The effect of buzzy and cold spray on pain, anxiety, and fear of children during venipuncture in pediatric emergency department in Turkey: A randomized controlled study. Journal of Pediatric Nursing, 68, e1-e7. https://doi.org/10.1016/j.pedn.2022.08.019

Sørensen, K., Skirbekk, H., Kvarstein, G., & Wøien, H. (2021). I don't want to think about it: A qualitative study of children (6-18 years) with rheumatic diseases and parents' experiences with regular needle injections at home. Pediatric Rheumatology, 19(1), 8. https://doi.org/10.1186/s12969-021-00495-4

Zhou, Z.-Y., Hu, L.-Y., Wang, M.-L., Li, S.-Q., & Zhou, L.-S. (2025). Effects of cold and vibration on venipuncture pain management in children aged 2-7 years old: Randomized controlled trial. JMIR Pediatrics and Parenting, 8, e67918. https://doi.org/10.2196/67918

Reading the NUR 4190 Module 5 assignment instructions

By the fifth module of NUR-4190 the appraised studies have to be pulled into one argument. Directions in many terms ask for a summary or evidence table, an overall verdict on its strength, its soundness and whether the studies agree, identification of gaps, and a conclusion about whether the evidence supports a change in practice. A few sections name the grading system you must apply, such as the Johns Hopkins evidence levels or the levels in your course text. Thomas Edison State University keeps the exact requirements in the Moodle classroom, including how many studies you must include and whether the table counts toward the page limit. The key requirement in every version is synthesis: say what the studies show together.

Inside the NUR 4190 Module 5 example

The example starts by restating the question and listing the six sources by type. An evidence table follows, ordered from the meta-analysis down to the qualitative study, with design, level, population, comparison and main finding for each. The paragraph after the table names two patterns across the studies and explains why they do not conflict. The strength section discusses blinding problems shared by every trial and identifies the most applicable study. A gaps section names three things the literature does not answer for this setting. The qualitative section turns the interview findings into a way of using the device. The verdict states the recommendation in three graded parts: direction, strength and applicability.

Reading the NUR 4190 Module 5 grading rubric

Synthesis papers are commonly graded on the evidence table, the synthesis itself, a judgment of how much the whole set of studies can bear, a list of what is still unknown, the conclusion about practice, and writing. Mentors give the most weight to synthesis and evaluation. A paper that summarizes each study in its own paragraph, even accurately, usually scores in the middle band, because it leaves the reader to do the integration. The top band generally requires comparison across studies, explanation of inconsistent findings, and a judgment of how confident the evidence allows the writer to be. The evidence table is checked for accuracy against the articles, so verify sample sizes, designs and findings before submitting.

NUR 4190 Module 5 help: mistakes that cost marks

The biggest risk in this module is writing six summaries in a row. Organize paragraphs by finding or theme, not by article, and let each paragraph cite several studies. Another common problem is ignoring results that do not fit, such as a trial where the intervention lost to another treatment; explain those results rather than leaving them out. Students also overstate strength, calling evidence conclusive when the trials share serious bias. Use the language of your evidence grading system. Check that your table and text agree on every number. Finally, end with a verdict the next module can use. If you have your appraised studies but need help pulling them into one synthesis, the desk can draft it to your directions.

Write yours, or have the desk draft it

This paper is an original model document written by our desk, not a submitted student paper and not an official Thomas Edison State University document. Read it for the moves, then write your own to the instructions in your classroom. If you want one built to your exact prompt and rubric, the first custom sample is free and arrives in 24 to 48 hours.

More NUR 4190 and Bachelor of Science in Nursing sample papers

NUR 4190 Module 5 questions, answered

Where can I find a free NUR 4190 Module 5 sample paper?

The full synthesis is on this page, with its evidence table, references and margin notes. It covers six studies on cold and vibration for children's venipuncture pain; follow its structure with the studies from your own search and appraisals.

What should an evidence table include in NUR-4190?

At minimum, each source's citation, design, level of evidence, sample, intervention and comparison, outcome measure and main finding. Some mentors also want a column for limitations. Order the rows by level of evidence so the reader sees the strongest sources first.

How is synthesis different from a literature review summary?

Summaries tell the reader one study at a time what was found. Synthesis lines studies up against one another, groups findings, explains disagreements, and states what the evidence shows as a whole and how strongly. If a paragraph discusses only one study, it is probably summary rather than synthesis.

What if the studies disagree?

Look for a reason: different populations, comparisons, outcome measures or settings often explain conflicting results. Report the disagreement, offer the most likely explanation, and say how it affects your recommendation. Leaving out inconvenient studies weakens the paper.

Can qualitative studies be part of the synthesis?

Yes. They will not prove an intervention works, but they explain patients' experiences and preferences, which helps you decide how to apply the quantitative findings. Integrate them in a separate paragraph or theme rather than mixing them into the effectiveness discussion.